Diagnostic and Therapeutic Approach in ANOCA Patients: Insights From the CADOSA Registry

Obstructive blockages on angiography provide an explanation for angina symptoms. However, patients with angina and non-obstructive coronary arteries (ANOCA) do not have a documented explanation for their symptoms and are frequently discharged with the non-diagnostic label of ‘non-cardiac chest pain’; despite the availability of functional angiography (provocative spasm and microvascular function testing) to exclude coronary vasomotor disorders. This study investigated the diagnostic approaches in ANOCA patients and compared management between ANOCA patients with a coronary vasomotor disorder diagnosis and those without.