IGF2BP2 promotes pancreatic carcinoma progression by enhancing the stability of B3GNT6 mRNA via m6A methylation.

Pei Cao,Yufan Wu,Ding Sun,Weigang Zhang,Junyi Qiu,Zuxiong Tang,Xiaofeng Xue,Lei Qin

Cancer medicine（2023）

引用 4|浏览4

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摘要

Elevated m6A levels promote PC progression. IGF2BP2 is a credible marker and modulates B3GNT6 mRNA stability, indicating that IGF2BP2 is a potential prognostic marker and therapeutic target in PC progression.

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关键词

B3GNT6,IGF2BP2,RNA methylation,epigenetic modification,pancreatic carcinoma

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