Micro ribonucleic acid-448 regulates zinc finger e-box binding homeobox 1 to inhibit the growth of breast cancer cells and increase their sensitivity to chemotherapy

•MicroRNA-448 expression decreased in Breast Cancer (BC) tissues and BC cells.•Zinc finger E-box Binding Homeobox 1 (ZEB1) was upregulated in BC tissues and cells.•Upregulation of miR-448 expression could inhibit the malignant behaviors of BC cells.•Upregulated miR-448 expression could enhance BC cells’ sensitivity to PTX or 5-FU.