Association of age and disease duration with comorbidities and disability: A study of the Swiss Multiple Sclerosis Registry

•Associations of age and MS duration with comorbidities and disability were explored using registry data.•Hypertension, diabetes, and cancer were associated with age, and cardiac disease was associated with both age and MS duration.•While having at least moderate gait disability was associated with both age and MS duration, severe was associated with MS duration only.•The spline analysis suggested a non-linear increase of having at least moderate gait disability with age.