Norbixin, a natural dye that improves serum lipid profile in rabbits and prevents LDL oxidation

Sabrina Somacal,Andréia Quatrin,Amanda R. Ruviaro,Lisiane Conte,Dariane T. da Silva,Miguel Roehrs,Marcelo L. da Veiga,Marta M.F. Duarte,Andreza F. de Bem,Paula R. Augusti,Tatiana Emanuelli

Food Research International（2022）

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摘要

•Norbixin (NBIX) inhibits human LDL oxidation in vitro.•NBIX reduces triglycerides and increases HDL levels of atherogenic rabbits (AR)•NBIX reduces oxidized LDL and autoantibodies levels in AR.•NBIX inhibits lipid and protein oxidation in the aortic tissue of AR.•NBIX counteracts changes in endogenous antioxidant defense systems of AR.

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关键词

Carotenoid,Annatto,Bixa orellana,Inflammation,Cholesterol,Oxidative stress,Atherosclerosis,Cardiovascular disease

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