Bioactive Curcumin and its Effects on Lowering Systemic Inflammation as Measured by CRP: A Systematic Review

Objectives: The purpose of this study was to analyze and evaluate evidence supporting curcumin lowering the systemic inflammatory marker, CRP in humans. Methods: A systematic literature search was completed using PubMed and MEDLINE databases. Results: After inclusion and exclusion criteria, 9 studies were evaluated, and the percent change of CRP blood levels was calculated and analyzed. Results: The results for these studies show strong statistical significance for the C3 complex with Bioperine and nano curcumin. Bioactive curcumin exhibits a higher percent decrease of blood level CRP than trials using only curcumin or turmeric. Conclusion: Overall bioactive curcumin/curcumin with Bioperine are alternative treatments for lowering the systemic inflammation marker, CRP.