Drug discovery in spinal cord injury-induced osteoporosis: a text mining-based study.

Chenfeng Wang,Yang Xu,Lin Han,Weiqing Wu,Xuhua Lu

Annals of translational medicine（2022）

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摘要

Taken together, siltuximab, olokizumab, clazakizumab and BAN2401 were first discovered to become the potential drugs for the treatment of SCI-induced OP. Drug discovery using text mining and pathway analysis is a significant way to investigate the pathomechanism of the disease while exploring existing drugs to treat the disease.

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关键词

Drug discovery,osteoporosis (OP),spinal cord injury (SCI),text mining

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