First detection and origin of multi-drug resistant Klebsiella pneumoniae ST15 harboring OXA-48 in South America

Cecilia Salazar,Verónica Antelo,Mariela Vieytes, Cristina Dávila,Fabio Grill,Antonio Galiana,Gregorio Iraola

Journal of Global Antimicrobial Resistance（2022）

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摘要

•First detection of Klebsiella pneumoniae epidemic clone ST15 in South America.•This clone originated from Spanish strains circulating since 2013.•Whole-genome sequencing revealed duplication of ESBL genes and OXA-48 carbapenemase.•Carriage in the urinary tract highlights the importance of active surveillance.

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关键词

OXA-48,Carbapenem resistance,Klebsiella pneumonia,Multi-drug resistance,Whole-genome sequencing

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