Development of a clinical prediction instrument to estimate risk of initial violent injury

•Interpersonal violent injuries are a public health emergency, with high rates of morbidity, mortality, and recidivism, and previously described risk characteristics have primarily focused on re-injury, violence perpetration, and firearms.•We described associations between sociobehavioral predictors and first-time violent injury victimization of all injury types, and developed an internally valid predictive risk score that grouped individuals by increasing prevalence of violent injury.•Our risk score has the potential to be utilized as a primary prevention strategy across multiple clinical settings, in order to prevent initial violent injury victimization.