Sequencing Impact and Prognostic Factors in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Cabazitaxel: A Systematic Review and Meta-Analysis
Urologic Oncology Seminars and Original Investigations(2023)
摘要
•Sequential therapy with cabazitaxel improves OS in post-docetaxel mCRPC patients.•Poor PS, visceral metastasis, and symptomatic disease were prognostic factors for OS.•Pretreatment high PSA, ALP, LDH or CRP were blood-based prognostic factors for OS.•Pretreatment low hemoglobin or albumin were also blood-based prognostic factors for OS.•These findings might help guide the clinical decision-making for the use of cabazitaxel.
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关键词
Metastatic castration-resistant prostate cancer,Cabazitaxel,Prognostic factor
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