Myoepithelioma of the upper lip: a case report

An 82-year-old female patient complained of a slow growing painless nodule on her upper lip with a 2-year history. Extraoral examination showed swelling in the left upper lip causing facial asymmetry. Intraoral examination revealed a mobile nodule of firm consistency covered by an intact mucosa with a light purplish color, measuring approximately 2 × 1 cm. The clinical differential diagnosis included mesenchymal tumor and salivary gland tumor. Excisional biopsy was performed, and microscopic examination showed well-circumscribed benign solid tumor characterized by island and cords of cells with myoepithelial differentiation showing spindle, plasmacytoid, and ephitelioid features. The cells were immunopositive for cytokeratin 14, S-100, and α-smooth muscle actin. The diagnosis of myoepithelioma was established. After 4 months of follow-up, satisfactory wound healing and no recurrences were detected. An 82-year-old female patient complained of a slow growing painless nodule on her upper lip with a 2-year history. Extraoral examination showed swelling in the left upper lip causing facial asymmetry. Intraoral examination revealed a mobile nodule of firm consistency covered by an intact mucosa with a light purplish color, measuring approximately 2 × 1 cm. The clinical differential diagnosis included mesenchymal tumor and salivary gland tumor. Excisional biopsy was performed, and microscopic examination showed well-circumscribed benign solid tumor characterized by island and cords of cells with myoepithelial differentiation showing spindle, plasmacytoid, and ephitelioid features. The cells were immunopositive for cytokeratin 14, S-100, and α-smooth muscle actin. The diagnosis of myoepithelioma was established. After 4 months of follow-up, satisfactory wound healing and no recurrences were detected.