Two New Terpenoid Glycosides from Isodon Macrocalyx.
Natural product research(2022)
摘要
One previously undescribed tricyclo-diterpenoid saponin (1), one undescribed dammarane triterpenoid saponin (2) and four known triterpenoids (3-6) were isolated from the aerial part of Isodon macrocalyx. Their structures were determined using 1 D- and 2 D-NMR, HRESIMS, and comparison of their spectroscopic data with previously reported data. The isolates were evaluated for their anti-HBV activity in vitro using the HBV transfected Hep G2.2.15 cell line. Compounds 2 and 3 exhibited moderate anti-HBV activity.
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关键词
Isodon macrocalyx,Lamiaceae,macrocalyxoside A,macrocalyxoside B,anti-HBV
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