Predictive Polygenic Score for Outcome after First-Line Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients Using Supervised Principal Component Analysis.

Hanla A Park,Dominic Edelmann,Federico Canzian,Tabitha A Harrison,Xinwei Hua,Qian Shi, Allison Silverman,Martin Schneider,Richard M Goldberg,Steven R Alberts,Michael Hoffmeister,Hermann Brenner,Andrew T Chan,Ulrike Peters,Polly A Newcomb,Jenny Chang-Claude

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology（2022）

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摘要

These results highlight the potential but also challenges in generating evidence for a predictive polygenic score for oxaliplatin efficacy.

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关键词

predictive polygenic score,colorectal cancer patients,colorectal cancer,cancer patients,first-line,oxaliplatin-based

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