TFG mutation induces haploinsufficiency and drives axonal Charcot-Marie-Tooth disease by causing neurite degeneration.

CNS neuroscience & therapeutics（2022）

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摘要

CMT2-related TFG mutation induces TFG haploinsufficiency within cells and drives disease by causing progressive neurite degeneration.

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关键词

axonal Charcot-Marie-Tooth,haploinsufficiency,neurite degeneration,tropomyosin-receptor kinase-fused gene,zebrafish model

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