Haemato-biochemical Alteration and Therapeutic Management of Canine Babesiosis

Canine babesiosis is one of the most common, globally existent, fast-spreading tick-borne haemoprotozoan disease caused by different species of Babesia.The present study discusses the clinico, haemato-biochemical changes and its therapeutic management in dogs infected with babesiosis.A 3.5 years old female Spitz having 10 kg body weight was presented to the TVCC, WBUAFS, Kolkata-37, West Bengal with a history of ectoparasitic infestation, inappetence for 5 days.Clinical examination revealed that, there were 103.4°F body temperature, tachycardia and increased respiratory rate.Closed clinical observation showed pale mucous membrane, severe dehydration, depression and swelling of lymph nodes.A peripheral blood smear and whole blood sample were sent to the laboratory for confirmatory diagnosis.The presence of pyriform-shaped organism, Babesia gibsoni on microscopical examination and correlation with haematobiochemical alteration confirmed the case as canine babesiosis associated with acute renal failure (ARF).Therapeutic management of acute renal failure was initiated along with specific treatment for canine babesiosis with triple drug therapy consisting of doxycycline @5 mg/kg b. wt., clindamycin @25 mg/kg b.wt.and metronidazole @15 mg/kg b. wt.orally twice daily for 14 consecutive days.Tick remover, injection ivermectin @0.2 mg/kg subcutaneously at weekly interval and for correction of anaemia haematinic syrup (Sharkoferrol) @5 mL daily orally were given.After two weeks of treatment, blood smear and blood sample were sent for re-examination.The report showed negative for any haemoprotozoa and the haemato-biochemical report also improved than earlier.