Double deficiency of cathepsin B and L in the mouse pancreas alters trypsin activity without affecting acute pancreatitis severity
Pancreatology(2022)
摘要
Double deletion of Ctsb and Ctsl in the mouse pancreas altered intrapancreatic trypsin activity but did not affect disease severity and inflammatory response after cerulein-induced AP.
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关键词
Cysteine proteases,Inflammation,Knockout mice,Lysosomal proteins
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