Double deficiency of cathepsin B and L in the mouse pancreas alters trypsin activity without affecting acute pancreatitis severity

Pancreatology(2022)

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摘要
Double deletion of Ctsb and Ctsl in the mouse pancreas altered intrapancreatic trypsin activity but did not affect disease severity and inflammatory response after cerulein-induced AP.
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关键词
Cysteine proteases,Inflammation,Knockout mice,Lysosomal proteins
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