Regulation of Cyclin D1 Degradation by Ubiquitin-Specific Protease 27X Is Critical for Cancer Cell Proliferation and Tumor Growth.

Molecular cancer research : MCR（2022）

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摘要

As a deubiquitinating enzyme, USP27X is a druggable target. Our study illuminates new avenues for therapeutic intervention in CCND1-driven cancers.

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关键词

cyclin d1 degradation,cancer cell proliferation,ubiquitin-specific

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