Finerenone prevents renal and vascular damage in a novel model of type 1 diabetes mellitus

Marta Sanz-Gomez,Elena Vega-Martin,Daniel Gonzalez-Moreno, Chiara Pizzamiglio,Francisco J. Manzano-Lista,Peter Kolkhof,Reinhold Kreutz,Maria S. Fernandez-Alfonso

Journal of hypertension（2022）

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摘要

Our data show that treatment with FIN improves renal and vascular damage in a new rat model of CKD with T1D. These beneficial effects associated with a reduction in inflammation and oxidative stress and was independent from changes in glucose homeostasis.

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finerenone prevents renal,diabetes mellitus

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