Effect of smoking on MUC1 expression in oral epithelial dysplasia, oral cancer, and irradiated oral epithelium

Bina Kashyap,Jopi J W Mikkonen,Tulika Bhardwaj,Hannah Dekker,Engelbert A J M Schulten,Elisabeth Bloemena,Arja M Kullaa

Archives of Oral Biology（2022）

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摘要

•Smoking accelerates MUC1 expression in the oral epithelium.•MUC1 depolarization is associated with smoking in epithelial dysplasia and OSCC.•Smoking complicates the oral mucosal adaptation after radiotherapy.•MUC1 expression in the oral epithelium is described first time with MUC1 score.

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关键词

Depolarization,Dysplasia,Oral cancer,Oral epithelium,MUC1,Irradiation

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