Proinflammatory changes in the maternal circulation, maternal-fetal interface, and placental transcriptome in preterm birth.

Camille Couture,Marie-Eve Brien,Ines Boufaied,Cyntia Duval,Dorothee Dal Soglio,Elizabeth Ann L Enninga,Brian Cox,Sylvie Girard

American journal of obstetrics and gynecology（2023）

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摘要

This work sheds light on changes within the immune system in preterm birth on multiple levels and compartments to help identify pregnancies at high risk of preterm birth and to discover novel therapeutic targets for preterm birth.

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关键词

RNA sequencing,inflammation,maternal circulation,maternal–fetal interface,placenta,preterm birth,transcriptomic profiles

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