The potential role of physical activity and a healthy diet in increasing nitric oxide during COVID-19 outbreak

The potential role of physical activity and a healthy diet in increasing nitric oxide during COVID-19 outbreak. This manuscript presents a perspective which provide new insights about the promising role of nitric oxide on COVID-19. Demonstration that nitric oxide was an important cornerstone against viral infections, including SARS-CoV-1 in 2009. Thus, given the concern that higher NO− could improve endothelial health and might be a protection factor against COVID-19, should we critically consider non-pharmacological strategies that increase NO− bioavailability as medicine for COVID-19? From this perspective, we highlight the potential effect of physical activity and healthy diet in stimulating the increase of NO− bioavailability.