A pediatric bithalamic high grade glioma with concomitant H3K27M and EGFR mutations.

Buket Kara, Ayça Ersen Danyeli,Mehmet Öztürk, Kübra Ertan, Yavuz Köksal

The Turkish journal of pediatrics（2022）

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摘要

EGFR mutation along with H3.1 K27M mutation is extremely rare in children to our knowledge. It should be kept in mind that if there is a possibility of targeted therapy, there may be a treatment option in this malignant disease with a poor prognosis.

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EGFR mutation,H3K27M mutation,bithalamic high grade glioma,children

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