Attenuating the atopic march: Meta-analysis of the dupilumab atopic dermatitis database for incident allergic events

Gregory P Geba,Dateng Li,Meng Xu,Kusha Mohammadi, Richa Attre,Marius Ardeleanu,Bret Musser

Journal of Allergy and Clinical Immunology（2023）

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摘要

The acquisition/worsening of allergic conditions suggestive of atopic march was observed in a pooled adult/adolescent AD study population with inadequately controlled AD. Treatment with dupilumab reduced new/worsened allergy events versus placebo; inclusion of IgE category change increased the apparent benefit.

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关键词

Atopic march,dupilumab,dermatitis, atopic,food hypersensitivity,eczema,antibodies, monoclonal,asthma,rhinitis, allergic,IgE responsiveness, atopic,meta-analysis

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