Clinical phenotypes of immediate first dose reactions to mRNA COVID-19: A multi-center latent class analysis.
The journal of allergy and clinical immunology. In practice（2022）
摘要
Three novel clinical phenotypes of immediate-onset reactions after dose one of mRNA COVID-19 vaccines were identified using latent class analysis: 1) Limited/Predominantly Cutaneous, 2) Sensory and 3) Systemic. While these clinical phenotypes may indicate differential mechanistic etiologies or associations with subsequent dose tolerance, most individuals proceeding to their second dose tolerated it.
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关键词
COVID-19,SARS-CoV-2,adverse reaction,allergy,anaphylaxis,cluster,hypersensitivity,mRNA,phenotype,vaccine
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