Functional Drug Sensitivity Screening of Bioprinted Tumor Organoids using High-Speed Live Cell Interferometry

Bowen Wang,Peyton J. Tebon,Alexander L. Markowitz,Graeme F. Murray,Huyen Thi Lam Nguyen,Nasrin Tavanaie,Thang L. Nguyen,Paul C. Boutros,Alice Soragni,Michael A. Teitell

Conference on Lasers and Electro-Optics（2022）

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摘要

We develop a method to apply a high-throughput quantitative phase imaging-based assay to functional biomass accumulation measurements of 3D tumor organoids with single-organoid resolution, and demonstrate its utility for drug screening and therapy selection.

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关键词

bioprinted tumor organoids,high-speed

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