Androgen Receptor as a Predictive Marker for Pathologic Complete Response in Hormone Receptor-Positive and HER-2-Negative Breast Cancer with Neoadjuvant Chemotherapy.

Eun-Gyeong Lee,Dong-Eun Lee,Hyun Hee Kim,Jai Hong Han,Seeyoun Lee,Han-Sung Kang,Eun Sook Lee,Heejung Chae,Sung Hoon Sim,Keun Seok Lee,Youngmee Kwon,So-Youn Jung

Cancer research and treatment（2023）

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摘要

AR expression is predominant in the HR+/HER2- subtype. AR- is significantly associated with the pCR rate in breast cancer patients, especially within HR+/HER2- subtype. When determining neoadjuvant chemotherapy for the HR+/HER2- subtype, AR expression can be considered as a pCR predictive marker.

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关键词

Androgen receptor,Breast neoplasms,Pathological complete response,Predictive

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