Internalizing symptoms associate with the pace of epigenetic aging in childhood

Marieke S. Tollenaar,Roseriet Beijers,Elika Garg,T.T. Thao Nguyen,David T.S. Lin,Julia L. MacIsaac,Idan Shalev,Michael S. Kobor,Michael J. Meaney, Kieran J. O’Donnell,Carolina de Weerth

Biological Psychology（2021）

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摘要

•Internalizing symptoms associate with epigenetic age acceleration in children.•Externalizing symptoms do not show this association.•Epigenetic age acceleration was based on the Horvath clock.•Childhood psychiatric symptoms were longitudinally assessed from age 2.5 to 10.

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关键词

Childhood,Internalizing symptoms,Externalizing symptoms,Epigenetic age acceleration,Biological aging

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