The high-intensity interval training mitigates the cardiac remodeling in spontaneously hypertensive rats

Letícia Estevam Engel, Francilene Lima Agostinho de Souza,Ines Cristina Giometti,Katashi Okoshi,Thaoan Bruno Mariano, Natalia Zamberlan Ferreira, Dyovana Gomes Pinheiro,Rafael Stuani Floriano,Andreo Fernando Aguiar,Antônio Carlos Cicogna,Ivan José Vechetti,Francis Lopes Pacagnelli

Life Sciences（2022）

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摘要

The influence of HIIT in the SHR model in the compensated hypertension phase generated an increase in cardiac hypertrophy, attenuated myocardial diastolic dysfunction, lowered blood pressure, improved functional capacity, and reversed the alteration in gene-encoding ATF2 protein.

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关键词

Physical exercise,Papillary muscles,MAP kinase signaling system,Hypertension

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