METTL7B serves as a prognostic biomarker and promotes metastasis of lung adenocarcinoma cells.
Annals of translational medicine（2022）
摘要
The reduction of METTL7B expression can prolong OS and DSS in LUAD patients. It may be utilized as a novel predictive biomarker of LUAD, and may be associated with immune infiltration of LUAD. Interfering with METTL7B expression can significantly cause inhibition of LUAD by modulating the ability of cells to proliferate and migrate. These results point to a possible target for developing anti-cancer therapies against LUAD.
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关键词
Methyltransferase like 7B (METTL7B),lung adenocarcinoma (LUAD),migration,prognosis,proliferation
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