Synthesis and computational characterization of aryl-fluorinated thiazoles: Experimental, DFT and molecular coupling studies

•Synthesis of fluorinated thiazole derivatives through the Hantzsch reaction.•NMR characterization of fluorinated thiazole derivatives.•Computational modeling of DFT chemical descriptors of synthesized thiazole derivatives.•Experimental NMR behavior rationalized by DFT chemical descriptors of synthesized thiazole derivatives.