SP3.1.9 Implementation of Colon Capsule Endoscopy (CCE) into the Clinical Setting – an Early Analysis

Abstract Aim Analysis of the collaborative implementation of colon capsule endoscopy (CCE) within NHS Greater Glasgow and Clyde Methods Database collected prospectively from first 175 patients referred. Demographic data collected for those undergoing CCE. Primary outcomes: negative, positive and incomplete/complications. Secondary outcomes: those requiring further investigation and outcomes (normal, abnormal and not performed). Abnormal findings: benign disease, dysplastic changes, malignancy and unresulted. Results Of the first 175 patients put forward for CCE, 128 (73%) underwent CCE: n=47 deemed unsuitable due to patient preference (n=21) and consultant decision (n=15). Mean age 57.8 (+/-13.9 SD), 56% female, 32% had ≥2 co-morbidities, and 6% having colorectal cancer family history. CCE findings: negative 16% (n= 21), positive 71% (n=91), incomplete/complications 12.5% (n= 16). Time from referral to CCE (Mean 130 days, Median 86 days). Time from CCE to reporting (Mean 9.4 day, Median 8 days). Time from referral (CCE report) to colonoscopy (Mean 127 days, Median 106 days). Colonoscopies still awaited (Mean 271 days, Median 269 days). 80% required further tests: 77% (n=98) colonoscopy or sigmoidoscopy and 4% (n=5) imaging. Results: 20% normal, 48% abnormal, 30% not yet performed and 2% inadequate/no longer required. Pathology: benign disease 38%, dysplastic changes 45%, invasive malignancy 9%, 9% unreported. Conclusions CCE has received significant investment to attempt to reduce the workload of endoscopy departments. However, 77% of the patients who underwent CCE require further investigation by scope. With an excellent safety profile, defining patient selection is key to optimising the clinical applicability of this evolving technology.