Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity

Allan H. Pang,Keith D. Green,Nishad Thamban Chandrika,Atefeh Garzan,Ankita Punetha,Selina Y. L. Holbrook,Melisa J. Willby,James E. Posey,Oleg V. Tsodikov,Sylvie Garneau-Tsodikova

European Journal of Medicinal Chemistry（2022）

Cited 5|Views20

Key words

Crystal structure,Drug resistance,Enhanced intracellular survival,Enzyme kinetics,Mycobacterium tuberculosis,Structure-activity relationship,Tuberculosis

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