Formation of Fluorovinyl Spiro-[imidazole-indene] and α‑Amino-β-naphthalenones via Rh(III)-Catalyzed Cascade C–H Functionalization

An efficacious method for building fluorovinyl spiro-[imidazole-indene] and α-amino-β-naphthalenone skeletons synchronously has been shown to consist of Rh­(III)-catalyzed C–H functionalization between 2H-imidazoles and difluoromethylene alkynes. This protocol demonstrates a practical and straightforward route for installing fluorine elements in the envisioned position of heterocyclic compounds.