First-in-human Intravesical Delivery of Pembrolizumab Identifies Immune Activation in Bladder Cancer Unresponsive to Bacillus Calmette-Guérin.

Khyati Meghani,Lauren Folgosa Cooley,Bonnie Choy,Masha Kocherginsky,Suchitra Swaminathan, Sabah S Munir,Robert S Svatek,Timothy Kuzel,Joshua J Meeks

European urology（2022）

引用 12|浏览13

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摘要

Direct application of pembrolizumab to the bladder is a promising alternative for non-muscle-invasive bladder cancer unresponsive to Bacillus Calmette-Guérin and should be investigated further.

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关键词

Bacillus Calmette-Guérin,Bladder cancer,Clinical trial,Digital spatial profiling,Intravesical pembrolizumab

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