The ingredients for an antimicrobial mathematical modelling broth

International Journal of Antimicrobial Agents(2022)

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摘要
Mathematical modelling has made significant contributions to the optimization of the use of antimicrobial treatments. This article discusses the key processes that such mathematical modelling should attempt to capture. In particular, this article highlights that the response of the host immune system requires quantification, and this is illustrated with a novel model structure.
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关键词
Mathematical modelling,Pharmacokinetics,Pharmacodynamics,Drug resistance
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