Discordance among assays for monitoring? Anticoagulation during extracorporeal life support.

Erik J Scott,Evan Rotar, Jolian J Dahl,Jared P Beller, Dustin T Money,W Z Chancellor,J H Mehaffey, Matt Morisette,Leora T Yarboro,Nicholas R Teman

Perfusion（2022）

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摘要

Nearly half of all aPTT and anti-Xa values were in discordant ranges and discordance is more likely as the time on ECLS and the INR level increase. The use of either assay in isolation to guide heparin anticoagulation may lead to misestimation of the degree of anticoagulation in complex ECLS patients.

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关键词

anticoagulation,extracorporeal life support,extracorporeal membrane oxygenation

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