A modified Delphi approach to develop a trial protocol for antibiotic de-escalation in patients with suspected sepsis.

Michael E Yarrington,Rebekah W Moehring,Michael Z David,Keith W Hamilton,Michael Klompas,Chanu Rhee,Kevin Hsueh,Elizabeth Dodds Ashley, Ronda L Sinkowitz-Cochran,Matthew Ryan,Deverick J Anderson

Antimicrobial stewardship & healthcare epidemiology : ASHE（2021）

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摘要

The modified Delphi approach is a useful method to achieve expert-level consensus in the absence of evidence suifficient to provide validated guidance. The Delphi approach allowed for flexibility in development of an opt-out trial protocol for sepsis antibiotic de-escalation. The utility of this protocol should be evaluated in a randomized controlled trial.

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关键词

Sepsis,antimicrobial stewardship,modified Delphi,patient safety,protocol development

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