Are Factor Xa Inhibitors Efficacious for Ischemic Stroke Prevention in Patients Without Atrial Fibrillation? Evidence From Randomized Clinical Trials.

Robert G Hart,Aristeidis H Katsanos,Kanjana S Perera,John W Eikelboom

The Canadian journal of cardiology（2023）

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摘要

Aggregate evidence on the basis of placebo comparisons from randomized trials supports the potential for oral factor Xa inhibitors to reduce ischemic stroke in patients without AF, but major bleeding is increased.

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关键词

apixaban,betrixaban,factor Xa inhibitors,intracranial bleeding,ischemic stroke,major bleeding,rivaroxaban,stroke

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