Curcumin conjugated dextran coated Fe3O4 Nanoparticles: Cytotoxic effect on lung cancer cell line A549

Abimanyu Sugumaran,Janani Sadhasivam,Pratiksha Gawas,Venkatramaiah Nutalapati, Rajesh Pandian,Sathish Kumar Perumal

Materials Science and Engineering: B（2022）

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摘要

•Curcumin loaded surface coated Fe3O4 magnetic nanoparticles grafted with dextran.•The impacts of the surface coating were correlated with the colloidal property.•High affinity of carboxyl group with positive iron surface confirms dextran layer.•No significant change in magnetization even after dextran coating.•Cytotoxicity tests shows significant cytotoxic effect on A549 cancer cells.

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关键词

A549 cell line,Curcumin,Dextran Coating,Fe3O4 nanoparticles,Functional Magnetic material,Lung Cancer

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