Effect of gap size of gold interdigitated electrodes on the electrochemical immunosensing of cardiac troponin-I for point-of-care applications

1Study of effect of electrode gap size in gold-coated IDEs towards efficient biosensing of cardiac troponin-I.2Implementation of electrochemical impedance spectroscopy and circuit simulation as effective tools for probing interface kinetics and sensor performance.3Approximately 71.4% and 50% enhancement in LoD and sensitivity observed upon scaling down gap size from 75 μm to 5 μm.4Linear detection range of troponin-I observed within 2–12 ng/mL.5Selection of suitable IDE geometry is essential in developing highly efficient and sensitive point-of-care unit for monitoring acute myocardial infraction.