Defective Mitochondrial Quality Control during Dengue Infection Contributes to Disease Pathogenesis

Bharati Singh,Kiran Avula,Shamim Akhtar Sufi, Nahid Parwin, Sayani Das,Mohd Faraz Alam, Subhashish Samantaray, Leelakrishna Bankapalli,Alankrita Rani,Kokavalla Poornima, Biswajita Prusty, Tareni P. Mallick, Shubham K. Shaw,Hiren Dodia, Shobhitendu Kabi, Trupti T. Pagad,Sriprasad Mohanty,Gulam Hussain Syed

Journal of Virology（2022）

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摘要

Many viruses target host cell mitochondria to create a microenvironment conducive to viral dissemination. Dengue virus also exploits host cell mitochondria to facilitate its viral life cycle.

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关键词

autophagy,dengue virus,inflammation,mitochondria,mitochondrial homeostasis,mitochondrial quality control,mitophagy,necrosis,mt-DNA

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