The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia Formation

Khurts Shilagardi,Eric D. Spear,Rachy Abraham,Diane E. Griffin,Susan Michaelis

mBio（2022）

引用 5|浏览16

暂无评分

摘要

The COVID-19 pandemic caused by the coronavirus SARS-CoV-2 has underscored the importance of understanding intrinsic cellular components that can be harnessed as the cell’s first line of defense to fight against viral infection. Our paper focuses on one such protein, the integral membrane protease ZMPSTE24, which interacts with interferon-inducible transmembrane proteins (IFITMs).

查看译文

关键词

COVID-19,SARS-CoV-2,ZMPSTE24,coronavirus,innate immune response,prelamin A,proteases,restriction factor

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要