Use of hyperbaric oxygen therapy to treat glans penis necrosis after prostatic artery embolization

We report a case of non-target embolization after PAE, which was treated with topical and systemic therapies including hyperbaric oxygenation. In this case, a 77-year-old man developed distal penile pain, hours after undergoing PAE. Within days, he experienced tissue necrosis involving the glans penis. Treatment with tramadol, tadalafil, topical lidocaine, and hyperbaric oxygenation was initiated, and the necrosis resolved after fifteen days. There are no standard treatments for penile necrosis after PAE. Hyperbaric oxygenation may be effective in reducing ischemia-related tissue loss and may be considered as a treatment option for penile necrosis that occurs as a complication of PAE.