Intravaginal Mesalamine Administration: A Novel Technique for Neovaginal Colitis

Objective: We aim to present a novel technique for the treatment of neovaginal diversion colitis (also known as neovaginal colitis). Case: OT is a 21-year-old cisgender female with a history of VACTERL who underwent a colonic vaginoplasty as an infant. She presented with symptoms indicative of and later diagnosed as neovaginal diversion colitis. The patient underwent a novel regimen of vaginal instillation of mesalamine followed by complete resolution of her symptoms. Discussion: The following case study demonstrates a potentially effective treatment for cases of neovaginal diversion colitis.