Leflunomide-induced pulmonary arterial hypertension: Case report and review of literature

Valentino Collini,Mauro Driussi,Chiara Nalli, Mara Baldassi,Emma Di Poi,Lorenzo Cereser, Francesco Giuliana,Vincenzo Patruno,Davide Stolfo,Gianfranco Sinagra,Massimo Imazio

Journal of Cardiology Cases（2022）

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摘要

Leflunomide, an isoxazole derivative, is a disease-modifying antirheumatic drug, that has successfully been used for the treatment of rheumatoid arthritis and psoriatic arthritis as a feasible alternative to methotrexate. Among side effects, pulmonary arterial hypertension (PAH) has been described in a few case reports.

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关键词

Leflunomide,Psoriatic arthritis,Drug-induced pulmonary hypertension

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