Hidden brain atrophy in ultra-high field MR images in a transgenic rat model of Huntington's disease

Ali Jahanshahi,Jackson T. Boonstra,Faisal Alosaimi,Ozlem Ozsoy,Stijn Michielse,Yasin Temel

Brain Disorders（2022）

引用 1|浏览5

暂无评分

摘要

•Neuronal shrinkage appears prior to striatal atrophy in tgHD rats.•The manifestation of striatal atrophy precedes cortical thinning in tgHD rats.•Volumetric changes were evident in conventional histology preparations.•In vivo ultra-high-field MR imaging failed to detect those volumetric changes.

查看译文

关键词

Huntington's disease,Striatum,Cerebral cortex,Degeneration,Magnetic resonance imaging,Transgenic rat model

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要