Click reaction inspired synthesis, antimicrobial evaluation and in silico docking of some pyrrole-chalcone linked 1,2,3-triazole hybrids

•A library of new pyrrole based chalcone linked 1,2,3 triazole hybrids was synthesized via click reaction.•In vitro antimicrobial evaluation of the synthesized compounds revealed good-to-moderate antimicrobial activity, with MIC values ranging from 0.0647 to 0.0127 µmol/mL.•Compound 7e with MIC of 0.0127 µmol/mL was found to be most potent against P. aeruginosa.•Molecular docking of the selected compounds against the 1KZN and 5TZ1 has been performed using iGemdock and the results supported the activity trends.