Po-675-08 a-g rna editing as a mediator of atrial fibrillation

RNA editing is an inflammatory modulator with high activity in the cardiovascular system. It is mainly active in noncoding genomic areas, but also invokes changes in coding genes, mimicking a mutation and altering protein function. Although RNA editing is implicated in atherosclerosis and cardiomyopathy, its role in atriopathy and AF is unknown.