Reduced polydopamine coated graphene for delivery of Hset1 antisense as A photothermal and gene therapy of breast cancer

Anahita Babavalian,Farnaz Sadat Mirzazadeh Tekie,Hossein Ayazi,Sheyda Ranjbar,Reyhaneh Varshochian,Mazda Rad-Malelkshahi,Omid Akhavan,Rassoul Dinarvand

Journal of Drug Delivery Science and Technology（2022）

引用 11|浏览7

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摘要

Breast cancer is the most prevalent type of cancer in women; hence, many researches have been focused on developing effective treatment protocols. In this study, a novel nanocarrier was fabricated for gene and photothermal combination cancer therapy by conjugating histone methyltransferase complex subunit SET1 (hSET1) on reduced polydopamine coated graphene oxide nanosheets (rGO-PDA).

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关键词

Graphene oxide,Polydopamine,Gene therapy,hSET1 antisense,Photothermal therapy

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