The protective effect of LCZ696 in coxsackievirus B3-induced acute viral myocarditis mice.

Xu Jing, Lian Hao,Lin Yuan-Nan,Liu Wei-Ke,Jin Lu-Shen,Ke Jin-Yan,Chen Yi-Lian,Qiu Yi-Xuan,Ge Li-Sha,Li Yue-Chun

ESC heart failure（2023）

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摘要

LCZ696 has a protective effect on AVMC by improving LVEF and reducing inflammation and apoptosis, which may be due to the inhibition of Drp1-mediated mitochondrial fission.

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关键词

AVMC,Apoptosis,Drp1,Inflammation,LCZ696,LVEF

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